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Everolimus mitigates the aberrant upregulation of BDNF in the primary auditory cortex of tinnitus rats.

Journal: Drug Design, Development and Therapy

Article Title: Everolimus Attenuates Salicylate-Induced Tinnitus-Like Behavior and Auditory Cortical Hyperexcitability

doi: 10.2147/DDDT.S632911

Figure Lengend Snippet: Everolimus mitigates the aberrant upregulation of BDNF in the primary auditory cortex of tinnitus rats.

Article Snippet: Subsequently, they were incubated overnight at 4°C with primary antibodies against phospho-mTOR (Ser2448) (ABclonal, Cat. AP1413), mTOR (ABclonal, Cat. A2445), BDNF (ABclonal, Cat. A4873), PSD95 (Abcam, Cat. ab18258), and Vinculin (ServiceBio, Cat. GB150068 ) as a loading control.

Techniques: